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Thimm D, Schiedel AC, Peti-Peterdi J, Kishore BK, Müller CE. The nucleobase adenine as a signalling molecule in the kidney. Acta Physiol (Oxf). 2015, 213, 808-818

Müller CE, Schiedel AC, Zimmermann H. PURINES 2014: nucleotides, nucleosides and nucleobases - international conference on signalling, drugs and targets. Purinergic Signal. 2014, 10, 651-656

Kishore, B., Zhang, Y., Gevorgyan, H., Kohan, D., Schiedel, A., Müller, C., Peti-Peterdi, J. Cellular Localization of Adenine Receptors (AdeR) in the Rat Kidney, and their Functional Significance in the Inner Medullary Collecting Duct. Am J Physiol Renal Physiol. 2013, 305, 1298-1305

Funke, M., Thimm, D., Schiedel, A.C., Müller, C.E. 8-Benzamidochromen-4-one-2-carboxylic Acids - Potent and Selective GPR35 Receptor Agonists. J. Med. Chem. 2013, 56, 5182-5197

Thimm, D., Knospe, M., Abdelrahman, A., Moutinho, M., Alsdorf, B.B.A., von  Kügelgen, I., Schiedel, A.C.*, Müller, C.E. Characterization of new G protein-coupled adenine receptors in mouse and hamster. Purinergic Signal. 2013, 9, 415-426

Knospe, M., Müller, C.E., Rosa, P., Abdelrahman, A., Thimm, D., Schiedel, A.C.* The rat adenine receptor: pharmacological characterization and mutagenesis studies to investigate its putative binding site. Purinergic Signal. 2013, 9, 367-381

Schiedel, A.C., Lacher, S.K., Linnemann, C., Knolle, P.A., Müller, C.E. Antiproliferative effects of selective adenosine receptor agonists and antagonists on human lymphocytes: evidence for receptor-independent mechanisms. Purinergic Signal. 2013, 9, 351-365

Seibt, B.F.,  Schiedel, A.C.#,  Thimm, D., Hinz, S., Sherbiny, F.F., Müller, C.E. The second extracellular loop of GPCRs determines subtype-selectivity and controls efficacy as evidenced by loop exchange studies at A2 adenosine receptors. Biochem. Pharmacol., 2013, 85, 1317–1329.

Thimm, D., Schiedel, A.C.*,  Sherbiny, F.F., Hinz, S., Hochheiser, K., Bertarelli, D. C.G., Maaß, A., Müller, C.E. Ligand-specific binding and activation of the human adenosine A2B receptor., Biochemistry, 2013, 52, 726-740.

Müller, C.E., Schiedel, A.C., and Baqi, Y. Allosteric modulators of rhodopsin-like G protein-coupled receptors: opportunities in drug development. Pharmacology & Therapeutics, 2012, 135, 292-315.

Schiedel, A.C.; Hinz, S.; Thimm, D.; Sherbiny, F.; Borrmann, T.; Maaß, A.; Müller, C.E. The four cysteine residues in the second extracellular loop of the human adenosine A2B receptor: role in ligand binding and receptor function. Biochem. Pharmacol. 2011, 82, 389-399.

Drabczyńska, A.; Yuzlenko, O.; Köse, M.; Paskaleva, M.; Schiedel, A.C.; Karolak-Wojciechowska; J.; Handzlik, J.; Karcz, T.; Kuder, K.; Müller, C.E.; Kieć-Kononowicz, K. Synthesis and biological activity of tricyclic cycloalkylimidazo-, pyrimido- and diazepinopurinediones. Eur. J. Med. Chem. 2011, 46, 3590-607.

Dettmann, S.; Schiedel, A.; Müller, C.E.; Gust, R. 2-Phenyl-1-[4-(2-piperidine-1-yl-ethoxy)benzyl]-1H-benzimidazoles as Ligands for the Estrogen Receptor: Synthesis and Pharmacological Evaluation. Bioorg. Med. Chem. 2010, 18, 4905-4916.

Borrmann, T.; Abdelrahman, A.; Volpini, R.; Lambertucci, C.; Alksnis, E.; Gorzalka, S.; Knospe, M.; Schiedel, A.C.; Cristalli, G.; Müller, C.E. Structure-activity relationships of adenine and deazaadenine derivatives as ligands for adenine receptors, a new purinergic receptor family. J. Med. Chem. 2009, 52, 5974-5989.

Sherbiny, F.F.; Schiedel, A.C.; Maaß, A.; Müller, C.E. Homology modelling of the human adenosine A2B receptor based on X-ray structures of bovine rhodopsin, the beta2-adrenergic receptor and the human adenosine A2A receptor. J. Comput. Aided Mol. Des. 2009, 23, 807-28.

Dyer, J.H.; Maina, A.; Gomez, I.D.; Cadet, M.; Oeljeklaus, S.; Schiedel, A.C. Cloning, expression and purification of an acetoacetyl CoA thiolase from sunflower cotyledon. Int. J. Biol. Sci. 2009, 5, 736-744.

Köse, M.; Schiedel, A.C. Nucleoside/nucleobase transporters - drug targets of the future? Future Med. Chem.  2009, 1, 303-326.

von Kügelgen, I.; Schiedel, A.C; Hoffmann, K.; Alsdorf, B.B.; Abdelrahman, A.; Müller, C.E. Cloning and Functional Expression of a Novel Gi Protein-Coupled Receptor for Adenine from Mouse Brain. Mol. Pharmacol. 2008, 73, 469-477.

Schiedel, A.C.; Meyer, H.; Alsdorf, B.B.A.; Gorzalka, S.; Brüssel, H.; Müller, C.E. [3H]Adenine is a suitable radioligand for the labeling of G protein-coupled adenine receptors but shows high affinity to bacterial contaminants in buffer solutions. Purinergic Signalling 2007, 3, 347-358.

Drabczyńska. A.; Müller, C.E.; Karolak-Wojciechowska, J.; Schumacher, B.; Schiedel, A.; Yuzlenko, O.; Kieć-Kononowicz, K. N9-benzyl-substituted 1,3-dimethyl- and 1,3-dipropyl-pyrimido[2,1-f]purinediones: synthesis and structure-activity relationships at adenosine A1 and A2A receptors. Bioorg. Med. Chem. 2007, 15, 5003-5017.

Drabczyńska, A.; Müller, C.E.; Schiedel, A.; Schumacher, B.; Karolak-Wojciechowska, J.; Fruziński, A.; Zobnina, W.; Yuzlenko, O.; Kieć-Kononowicz, K. Phenylethyl-substituted pyrimido[2,1-f]purinediones and related compounds: structure-activity relationships as adenosine A(1) and A(2A) receptor ligands. Bioorg Med Chem. 2007, 15, 6956-6974.

Schiedel, A.C.; Oeljeklaus, S.; Minihan, P.; Dyer, J.H. Cloning, expression, and purification of glyoxysomal 3-oxoacyl-CoA thiolase from sunflower cotyledon. Protein Expr. Purif. 2004, 33, 25-33.

Mayer, T.; Meyer, M.; Janning, A.; Schiedel, A.C. and Barnekow, A. A mutant form of the rho protein can restore stress fibers and adhesion plaques in v-src transformed fibroblasts. Oncogene 1999, 18, 689-701.

Schiedel, A.C.; Barnekow, A.; Mayer, T. Nucleotide induced conformation determines posttranslational isoprenylation of the ras related rab6 protein in insect cells. FEBS Lett. 1995, 376, 113-119.


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