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Prof. Dr. Michael Gütschow

Universität Bonn
Pharmazeutisches Institut
Pharmazeutische & Medizinische Chemie
An der Immenburg 4
D-53121 Bonn
Deutschland

Tel: +49 228 732317
Fax: +49 228 732567

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Poster und Vorträge

  • The 58th Japanese Peptide Symposium - Online 2021
    S. Konno, K. Kobayashi, M. Senda, Y. Funai, Y. Seki, I. Tamai, L. Schäkel, K. Sakata, T. Pillaiyar, A. Taguchi, A. Taniguchi, M. Gütschow, C. Müller, K. Takeuchi, M. Hirohama, A. Kawaguchi, M. Kojima, T. Senda, Y. Shirasaka, W. Kamitani, Y. Hayashi:
    3CL Protease Inhibitors with an Arylketone Warhead Group as Anti-SARS-CoV-2 Agents.
  • DPhG-Annual Meeting – Online 2021
    C. Steinebach:
    Development of PROTAC Tools to Study Cancer Cell Biology.
  • Conference Synthesis and Analysis of Drugs – Online 2021
    M. Gütschow:
    PROTACs for the Degradation of Cyclin-dependent Kinases and Beyond.
  • EFMC-ISMC 2021, XXVI EFMC International Symposium on Medicinal Chemistry - Online 2021
    C. Steinebach, Y.L.D. Ng, A. Bricelj, I. Sosič, J. Krönke, M. Gütschow:
    PROTAC-Mediated Inactivation of E3 Ligases - From Tools to Cancer Treatment.
  • EFMC-YMCS 2021, 8th EFMC Yound Medicinal Chemist's Symposium - Online 2021
    C. Steinebach, Y.L.D. Ng, A. Bricelj, I. Sosič, J. Krönke, M. Gütschow:
    PROTAC-Mediated Inactivation of E3 Ligases - From Tools to Cancer Treatment.
  • The 45th FEBS Congress - Online 2021
    I. Sosič, C. Steinebach, A. Bricelj,  Y. L. D. Ng,   M. Gobec, J. Krönke, R. J. Pieters, M. Anderluh, M. Gütschow:
    PROTACS as Tools for the Modulation of Pharmacological Targets.
  • European School of Medicinal Chemistry - Online 2021
    M. Gütschow:
    Towards the Development of PROTACs for the Degradation of CDK6 and Beyond.
  • Frontiers in Medicinal Chemistry - Online 2021
    L. P. Vu, C. Steinebach, A. Bricelj, I. Sosič, M. Gütschow:
    Synthesis of Novel Building Blocks for VHL-based PROTACs.
  • Frontiers in Medicinal Chemistry - Online 2021
    C. Steinebach, D. Ferber, Y. L. D. Ng, A. Bricelj, M. Jamali, R. Kuchta, I. Sosič, M. D. Hartmann, J. Krönke, M. Gütschow:
    Design, Synthesis and Biomedical Investigation of New E3 Ligase Modulators.
  • Frontiers in Medicinal Chemistry - Online 2021
    L. Schäkel, J. Breidenbach, C. Lemke, T. Pillaiyar, G. Al Hamwi, M. Diett, R. Gedschold, V. Lopez, S. Mirza, V. Namasivayam, A. C. Schiedel, K. Sylvester, D. Thimm, C. Vielmuth, L. P. Vu, M. Zyulina, M. Gütschow, C. E. Müller:
    Design and Development of Potent Inhibitors of the SARS-CoV-2 Main Protease.
  • Frontiers in Medicinal Chemistry - Online 2021
    C. Lemke, J. Breidenbach, L. Schäkel, T. Pillaiyar, G. Al Hamwi, M. Diett, R. Gedschold, V. Lopez, S. Mirza, V. Namasivayam, A. C. Schiedel, K. Sylvester, D. Thimm, C. Vielmuth, L. P. Vu, M. Zyulina, C. E. Müller, M. Gütschow:
    Establishment and Optimization of a SARS-CoV-2 Main Protease in Vitro Assay.
  • DECHEMA Biotechnologies, Advances in Chemical Biology Virtual Conference - Online 2021
    C. Steinebach:
    Repurposing Different E3 Ligases for Targeted Degradation.
  • 2nd Alpine Winter Conference on Medicinal and Synthetic Chemistry - St. Anton 2020
    A. Bricelj, E. M. Loi, M. Gobec, C. Steinebach, M. Gütschow, R. J. Pieters, I. Sosič, M. Anderluh:
    Development of OSMI-4-Based Biochemical Probes for OTG.
  • 2nd Alpine Winter Conference on Medicinal and Synthetic Chemistry - St. Anton 2020
    C. Steinebach:
    Four E3 Ligases, One Target: Towards Novel CDK6 PROTACs.
  • American Society of Hematology (ASH) 61st Annual Meeting - Orlando 2019
    Y. L. D. Ng, E. Ramberger, S. Bohl, O. Popp, I. Bauhuf, A. Dolnik, C. Steinebach, D. Miller, M. Gütschow, L. Bullinger, P. Mertins, J. Krönke:
    Quantitative Proteomic Analysis of Relapsed Multiple Myeloma Identifies CDK6 Upregulation As a Potential Targetable Resistance Mechanism for Lenalidomide.
  • SancaMedChem, The Sao Carlos Medicinal Chemistry Meeting - Sao Carlos 2019
    M. Gütschow:
    Novel Cathepsin B Inhibitors with Inversely Oriented Warheads.
  • EFMC-ASMC '19, EFMC International Symposium on Advances in Synthetic and Medicinal Chemistry - Athens 2019
    L. P. Vu, C. Steinebach, S. Lindner, J. Krönke, M. Gütschow:
    Synthesis of Functional Building Blocks for PROTACs.
  • EFMC-ASMC '19, EFMC International Symposium on Advances in Synthetic and Medicinal Chemistry - Athens 2019
    C. Lemke, C. Breuer, T. Schirmeister, M. Gütschow:
    Towards Activity-Based Probing of Rhodesain: A Vinyl Sulfone derived Inhibitor with a Bimodal Fluorescence Label.
  • DPhG Jahrestagung - Heidelberg 2019
    M. Gütschow:
    Novel Cathepsin B Inhibitors with Inversely Oriented Warheads.
  • II DFG-FAPESP Workshop - Protease Research in Chemistry and Biology - Mainz 2019
    M. Gütschow:
    Symmetry of Ligands: Matriptase-2 Inhibitors as a Case Study in Drug Design.
  • The 23rd International Symposium on Radiopharmaceutical Sciences (ISRS 2019) - Beijing 2019
    M. Laube, M. Frizler, R. Wodtke, C. Neuber, R. Bergmann, M. Bachmann, M. Gütschow, J. Pietzsch, R. Loeser:
    Synthesis and Radiopharmacological Evaluation of a C-11-Labeled Azadipeptide Nitrile Inhibitor for Targeting Cysteine Cathepsins.
  • EFMC-ASMC, Joint Symposium on Medicinal Chemistry Frontiers - Krakow 2019
    I. Sosic, C. Steinebach, S. Lindner, A. Bricelj, Y. L. D. Ng, J. Krönke, M. Gütschow:
    A Chemical Toolbox for Cereblon-Directed PROTACs.
  • EFMC-ASMC, Joint Symposium on Medicinal Chemistry Frontiers - Krakow 2019
    C. Steinebach, S. Lindner, I. Sosic, J. Krönke, M. Gütschow:
    Small-Molecule Modulation of Cereblon Protein Level.
  • EFMC-ASMC, Joint Symposium on Medicinal Chemistry Frontiers - Krakow 2019
    C. Steinebach:
    Short Lecture: Small-Molecule Modulation of Cereblon Protein Level.
  • Lecture, Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Prague - December 04, 2018
    M. Gütschow:
    Novel Peptidomimetics as Inhibitors of Human Proteases.
  • American Society of Hematology Annual Meeting - San Diego 2018
    S. Lindner, C. Steinebach, N. Udeshi, D. Mani, H. Kehm, S. Köpff, S. A. Carr, M. Gütschow, J. Krönke:
    Pomalidomide-Based Homo-PROTACs for the Chemical Knockdown of Cereblon. ref. Blood, 2018, 132, 260.
  • V All Russian International Conference on Organic Chemistry - Vladikavkas 2018
    M. Gütschow:
    Design and Synthesis of Novel Peptidomimetics as Inhibitors of Human Proteases.
  • Lecture, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, Moscow - September 15, 2018
    M. Gütschow:
    Design and Synthesis of Novel Peptidomimetics as Inhibitors of Human Proteases.
  • EFMC-ISMC 2018, XXV EFMC International Symposium on Medicinal Chemistry - Ljubljana 2018
    J. Küppers, M. Hympánová, G. Schnakenburg, M. Gütschow:
    Design, Synthesis and Biological Evaluation of Davidson-like Imidazole Derivatives.
  • EFMC-ISMC 2018, XXV EFMC International Symposium on Medicinal Chemistry - Ljubljana 2018
    C. Steinebach:
    Short Lecture: Gemini-Type PROTACs: a Small Molecule -Based Strategy for Self-Directed Inactivation of Cereblon.
  • EFMC-ISMC 2018, XXV EFMC International Symposium on Medicinal Chemistry - Ljubljana 2018
    J. Küppers, S. Annala, T. Benkel, E. Kostenis, M. Gütschow:
    Towards G Protein Inhibition by Small Molecules: Preparation of BIM-46174 Fragments.
  • EFMC-ISMC 2018, XXV EFMC International Symposium on Medicinal Chemistry - Ljubljana 2018
    C. Steinebach, S. Lindner, J. Krönke, M. Gütschow:
    Gemini-Type PROTACs for the Chemical Knockdown of Cereblon.
  • 2nd WG Meeting - MuTaLig COST Action - La Laguna, Tenerife, 2018
    M. Gütschow:
    Symmetry of Ligands: Matriptase-2 Inhibitors as a Case Study in Drug Design.
  • 3rd International Electronic Conference on Medicinal Chemistry - Online 2017
    J. Küppers, M. Gütschow:
    A Synthetic Entry to Amino Acid Derivatives through Davidson-like Heterocyclization.
  • 3rd International Electronic Conference on Medicinal Chemistry - Online 2017
    F. Kohl, M. Gütschow:
    Fragments of Peptoid 1: Synthesis of N-Substituted Glycine Monomers.
  • 3rd International Electronic Conference on Medicinal Chemistry - Online 2017
    M. Mangold, M. Gütschow, M. Stirnberg:
    A Short Peptide Inhibitor as an Activity-Based Probe for Matriptase-2.
  • International Symposium on GPCRs and G Protein "turning scientific discoveries with cutting edge methods to cutting edge science" - Königswinter 2017
    A.-M. Beckmann, E. Maurer, M. Mangold, N. Furtmann, J. Bajorath, J. Walter, C. Becker-Pauly, M. Gütschow, M. Stirnberg:
    Kunitz-type inhibitors targeting matriptase-2: Promising therapeutics for iron overload diseases.
  • International Symposium on GPCRs and G Protein "turning scientific discoveries with cutting edge methods to cutting edge science" - Königswinter 2017
    J. Küppers, S. Annala, T. Benkel, M. Kuschak, A. Abdelrahman, C. E. Müller, E. Kostenis, M. Gütschow:
    Heterocyclized Dipeptide Derivatives as Inhibitors for Heterotrimeric G proteins.
  • EFMC-ASMC´17, VII International Symposium on Advances in Synthetic and Medicinal Chemistry - Vienna 2017
    C. Breuer, A. C. Schulz-Fincke, U. Bartz, M. Gütschow:
    O-Aryl-N-Dipeptidyl Carbamates as Inhibitors of Cathepsins.
  • 53rd Gordon Research Conference Heterocyclic Compounds - USA 2017
    J. Küppers, S. Annala, T. Benkel, M. Kuschak, A. Abdelrahman, C. E. Müller, E. Kostenis, M. Gütschow:
  • Heterocyclized Dipeptide Derivatives as Inhibitors for Heterotrimeric G Proteins.
    Lecture, GDCh-Ortsverband Aalen-Ostalb, Hochschule Aalen - 2017
    M. Gütschow:
    Novel Cathepsin B Inhibitors with Inversely Oriented Warheads.
  • Keystone Conference - G Protein-Coupled Receptors: Structure, Signaling and Drug Discovery - 2016
    K. Büllesbach, O. M. Bautista-Aguilera, R. Schröder, M. Gütschow, E. Kostenis:
    Elucidating the mode of action of novel indole antagonists of OXE-R.
  • DPhG Jahrestagung 2016 - München
    C. Steinebach, M. Gütschow:
    Synthetic phthalimide conjugation strategies for PROTAC development.
  • 2nd International Symposium: Protease World in Health & Disease - Kiel 2016
    A. M. Beckmann, K. Glebov, O. Merkel, J. Walter, M. Mangold, F. Schmidt, C. Becker-Pauly. M. Gütschow, M. Stirnberg:
    The amyloid precursor protein as a substrate for the cell surface serine protease matriptase-2.
  • 2nd International Symposium: Protease World in Health & Disease - Kiel 2016
    M. Mangold, D. Häußler, A.-M. Beckmann, A. Gitlin, K. Rolka, M. Gütschow, M. Stirnberg:
    Activity based probes for detection of active matriptase-2.
  • 2nd International Symposium: Protease World in Health & Disease - Kiel 2016
    A.-M. Beckmann, E. Maurer, V. Lülsdorff, A. Wilms, N. Furtmann, J. Bajorath, M. Gütschow, M. Stirnberg:
    Targetting the type II transmembrane serine protease martiptase-2 by Kunitz-type inhibitors: New therapeutic options for iron overload disease.
  • Lecture, Molecular Life Seminar at Jakobs University Bremen - September 27, 2016
    M. Gütschow:
    Activity-Based Probes and Cathepsin B Inhibitors with Inversely Oriented Warheads.
  • 34th European Peptide Symposium & 8th International Peptide Symposium - Leipzig 2016
    M. Gütschow:
    Matriptase-2 as a Target for Peptidomimetic Tool Compounds: Symmetric and Asymmetric Ligands, Inactivators & Activity Based Probes. ref. J. Pept. Sci. 2016, 22, S43.
  • 34th European Peptide Symposium & 8th International Peptide Symposium - Leipzig 2016
    A. Gitlin-Domagalska, D. Debowski, N. Ptaszynska, A. Legowska, M. Stirnberg, M. Gütschow, K. Rolka:  Designing and Chemical Syntheses of Selective Matriptase-2 Inhibitors Based on Trypsin Inhibitor SFTI-1 Isolated from Sunflower.
  • 8th Conference Chemistry towards Biology - Brno 2016
    M. Gütschow:
    Limiting the Number of Possible Pocket Occupations by Introducing Symmetry into Ligands: Development of Protease Inhibitors.
  • European Iron Club Annual Meeting - Innsbruck 2016
    M. Stirnberg, A.-M. Beckmann, E. Maurer, V. Lülsdorff, A. Wilms, N. Furtmann, J. Bajorath, M. Gütschow:
    Short lecture: En route to new therapeutic options for iron overload diseases: Matriptase-2 as a target for Kunitz-type inhibitors. 2nd Prize in the Oral Presentation Category
  • European Iron Club Annual Meeting - Innsbruck 2016
    M. Mangold, D. Häußler, A.-M. Beckmann, M. Gütschow, M. Stirnberg:
    Imaging of matriptase-2 by activity-based probes.
  • European Iron Club Annual Meeting - Innsbruck 2016
    A.-M. Beckmann, K. Glebov, J. Walter, O. Merkel, M. Mangold, F. Schmidt, C. Becker-Pauly, M. Gütschow, M. Stirnberg:
    Kunitz domain-containing APP is protected from matriptase-2-mediated proteolysis by inhibiting matriptase-2.
  • Polyamines in Parasites and Pathogenic Microorganisms - Bonn 2016
    J. Schmitz, U. Bartz, M. Gütschow:
    Short lecture: Design and development of inhibitors for cysteine cathepsins.
  • Frontiers in Medicinal Chemistry - Bonn 2016
    A.-M. Beckmann, E. Maurer, V. Lülsdorff, A. Wilms, N. Furtmann, J. Bajorath, M. Gütschow, M. Stirnberg:
    Short lecture: En route to new therapeutic options for iron overload diseases: Matriptase-2 as a target for Kunitz-type inhibitors.
  • Frontiers in Medicinal Chemistry - Bonn 2016
    A.-C. Schulz-Fincke, A. S. Tikhomirov, M. Gütschow:
    Design and evaluation of a new activity-based probe for elastase.
  • Frontiers in Medicinal Chemistry - Bonn 2016
    C. Breuer, A.-C. Schulz-Fincke, J. Schmitz, U. Bartz, M. Gütschow:
    Synthesis of biologically active O-aryl-N-dipeptidyl carbamates.
  • Frontiers in Medicinal Chemistry - Bonn 2016
    J. Schmitz, T. Li, U. Bartz, M. Gütschow:
    Combining the dipeptide nitrile scaffold with an occluding loop recognition element by click chemistry: design of inhibitors for human cathepsin B.
  • Frontiers in Medicinal Chemistry - Bonn 2016
    N. Furtmann, D. Häußler, T. Scheidt, M. Stirnberg, T. Steinmetzer, J. Bajorath, M. Gütschow:
    Limiting the number of potential binding modes by introducing symmetry into ligands: structure-based design of inhibitors for trypsin-like serine proteases.
  • Frontiers in Medicinal Chemistry - Bonn 2016
    J. Küppers, J. Palus, M. Giurg, J. Skarzewski, M. Gütschow:
    Labeling of ebselen: convergent synthesis of two ebselen-biotin heterodimers.
  • Frontiers in Medicinal Chemistry - Bonn 2016
    C. Steinebach, A.-C. Schulz-Fincke, M. Gütschow:
    In situ generation and trapping of thioimidates: an intermolecular tandem reaction to 4-acylimino-4H-3,1-benzothiazines.
  • Frontiers in Medicinal Chemistry - Bonn 2016
    M. Stirnberg, A.-M. Beckmann, K. Glebov, J. Walter, O. Merkel, M. Mangold, F. Schmidt, C. Becker-Pauly, M. Gütschow:
    A new link between Alzheimer's disease and iron: The intact Kunitz domain protects the amyoid precursor protein from being processed by the proteolytic regulator of iron homeostasis matriptase-2.
  • Frontiers in Medicinal Chemistry - Bonn 2016
    M. Mangold, D. Häußler, A.-M. Beckmann, M. Gütschow, M. Stirnberg:
    Application of the first activity-based probe for active matriptase-2, the proteolytic regulator of iron homeostasis.
  • Frontiers in Medicinal Chemistry - Bonn 2016
    D. Häußler, M. Mangold, N. Furtmann, M. Stirnberg, M. Gütschow:
    Structure-activity relationships of phosphono dipeptides as irreversible inhibitors of matriptase-2.
  • 1st International Electronic Conference on Medicinal Chemistry - 2015
    J. Küppers, J. Palus, M. Giurg, J. Skarzewski, M. Gütschow:
    Convergent Synthesis of a Linker-Connected Fluorescent Ebselen-Coumarin Heterodimer.
  • 1st International Electronic Conference on Medicinal Chemistry - 2015
    N. Furtmann, D. Häußler, T. Scheidt, M. Stirnberg, T. Steinmetzer, J. Bajorath, M. Gütschow:
    Limiting the Number of Potential Binding Modes by Introducing Symmetry into Ligands: Structure-Based Design of Inhibitors for Trypsin-Like Serine Proteases.
  • 1st International Electronic Conference on Medicinal Chemistry - 2015
    J. Schmitz, N. Furtmann, M. Ponert, U. Bartz, J. Bajorath, M. Gütschow:
    Active Site Mapping of Human Cathepsin F with Dipeptide Nitrile Inhibitors.
  • ChemBioMed V - Molecular Switches in Disease & Development - Mainz 2015
    M. Gütschow:
    Novel Cathepsin B Inhibitors with Inversely Oriented Warheads.
  • International Congress on Heterocyclic Chemistry “KOST-2015” – Moscow 2015
    A. S. Tikhomirov, A. C. Schulz-Fincke, M. Gütschow, A. E. Shchekotikhin:
    A Synthesis of New Fluorescent-Labeled Elastase Inhibitors.
  • Annual Meeting of the German Pharmaceutical Society – Düsseldorf 2015
    A. C. Schulz-Fincke, A. S. Tikhomirov, M. Gütschow:
    A Sulfonyloxyphthalimide Derivate as an Activity-based Probe for Elastase.
  • Annual Meeting of the German Pharmaceutical Society – Düsseldorf 2015
    J. Küppers, J. Palus, M. Giurg, J. Skarzewski, M. Gütschow:
    Convergent Synthesis of a Linker-Connected Fluorescent Ebselen-Coumarin Heterodimer.
  • Annual Meeting of the German Pharmaceutical Society – Düsseldorf 2015
    M. D. Mertens, A. Bierwisch, T. Li, M. Gütschow, T. Wille, P. W. Elsinghorst:
    A Novel Fluorogenic Probe for the Investigation of Free Thiols: Application to Kinetic Measurements of Acetylcholinesterase Activity.
  • Annual Meeting of the German Pharmaceutical Society – Düsseldorf 2015
    K. Büllesbach, O. M. Bautista-Aguilera, R. Schröder, M. Gütschow, E. Kostenis:
    Differential Modulation of Gbetagamma Effectors by Ligands Targetting GPCRs.
  • IRTG Summer School on Proteases and Pathophysiology – Kiel 2015
    A. M. Beckmann, K. Glebov, O. Merkel, J. Walter, M. Mangold, F. Schmidt, C. Becker-Pauly. M. Gütschow, M. Stirnberg:
    The intact Kunitz domain protects the amyloid precursor protein from being processed by matriptase-2
  • IRTG Summer School on Proteases and Pathophysiology – Kiel 2015
    M. Mangold, A. M. Beckmann, M. Gütschow, M. Stirnberg:
    Imaging and Purification of Active Matriptase-2 by a Novel Activity-based Probe.
  • 23rd Polish Peptide Symposium – Spała near Łódź 2015
    M. Gütschow:
    Limiting the Number of Possible Pocket Occupations by Introducing Symmetry into Ligands: From Peptidic to Malonic Acid-Derived Protease Inhibitors.
  • 2nd European Conference on Natural Products – Frankfurt/Main 2015
    J. Schrör, P. Hufendiek, S. Kehraus, M. Gütschow, G. M. König:
    Secondary Metabolites of the Fungus Stemphylium globuliferum and their Biological Activity.
  • 2nd European Conference on Natural Products – Frankfurt/Main 2015
    P. Hufendiek, S. Kehraus, M. Gütschow, G. M. König:
    Epipyrones from the Marine-Derived Fungus Epicoccum nigrum Inhibit the Proteases Cathepsin K and S.
  • 1st International Conference of the Marine Fungal Natural Products consortium – Nantes 2015
    J. Schrör, P. Hufendiek, S. Kehraus, M. Gütschow, G. M. König:
    Secondary Metabolites of the Fungus Stemphylium globuliferum and their Biological Activity.
  • 1st International Conference of the Marine Fungal Natural Products consortium – Nantes 2015
    P. Hufendiek, S. Kehraus, M. Gütschow, G. M. König:
    Epipyrones from the Marine-Derived Fungus Epicoccum nigrum Inhibit the Proteases Cathepsin K and S.
  • 9th European Conference on Marine Natural Products – Glasgow 2015
    P. Hufendiek, S. Kehraus, M. Gütschow, G. M. König:
    Epipyrones from the Marine-Derived Fungus Epicoccum nigrum Inhibit the Proteases Cathepsin K and S.
  • Lecture, Institute of Pharmacy, Freie Universität Berlin - July 07, 2015
    M. Gütschow:
    Design, Synthesis and Evaluation of Azapeptide Nitriles as Inhibitors of Human Cysteine Cathepsins.
  • IX. Joint Meeting in Medicinal Chemistry - Athens 2015
    M. Gütschow:
    Azapeptide Nitriles as Inhibitors of Human Cysteine Cathepsins.
  • Enzymes in Drug Discovery (Catalyses in Drug Discovery Summit) - San Diego, USA, 2015
    M. Sheikh, M. Steinkrüger, D. Augner, M. Gütschow, S. Herzig, H.-G. Schmalz, M. Pietsch:
    Identification and Kinetic Characterization of 2-Benzyl-3-phenylisoindolinones as Novel Inhibitors of Human Cholesterol Esterase.
  • 33rd European Peptide Symposium - Sofia, 2014
    A. Gitlin, D. Dębowski, N. Karna, A. Łęgowska, M. Stirnberg, M. Gütschow, K. Rolka:
    Analogues of Trypsin Inhibitor SFTI-1 and their Inhibitory Activity against Matriptase-2.
    ref. J. Pept. Sci. 2014, 20, S216.
  • Lecture at Wroclaw University of Technology, Department of Organic Chemistry - Wroclaw, November 04, 2014
    M. Gütschow:
    Design, Synthesis and Evaluation of Azapeptide Nitriles as Inhibitors of Human Cysteine Cathepsins.
  • Annual Meeting of the German Pharmaceutical Society - Frankfurt/Main 2014
    K. Büllesbach, O. M. Bautista, S. Blättermann, R. Schröder, C. D. Weaver, M. Gütschow, E. Kostenis:
    Label-free dynamic mass redistribution analysis of 5-oxo-ETE receptor signaling via Galphai and Gbetagamma signaling routes.
  • 6th Polish Meeting on Medicinal Chemistry - Lublin, 2014
    M. Gütschow:
    Inhibition of Human Cysteine Cathepsins by Azapeptide Nitriles.
  • EFMC-ISMC 2014, XXIII International Symposium on Medicinal Chemistry - Lisbon, 2014
    N. Furtmann, D. Häußler, J. Bajorath, M. Gütschow:
    Structure-Based Design, Synthesis and Biological Evaluation of Symmetric Bisbenzamidines as Inhibitors of Matriptase-2.
  • EFMC-ISMC 2014, XXIII International Symposium on Medicinal Chemistry - Lisbon, 2014
    D. Häußler, M. Gütschow:
    Synthesis and Characterization of a Fluorescent-Labeled Bisbenzguanidine as Activity-Based Probe for Matriptase-2.
  • European Iron Club Meeting - Verona, 2014
    M. Stirnberg, E. Maurer, A.-M. Beckmann, V. Lülsdorff, M. Gütschow:
    Identification and Characterization of Natural Inhibitors of Matriptase-2, the Regulatory Protease of Iron Homeostasis: Perspectives for Potential Treatments of Iron Overload Diseases.
  • European Iron Club Meeting - Verona, 2014
    A.-M. Beckmann, V. Lülsdorff, M. Mangold, M. Gütschow, M. Stirnberg:
    Kinetic Analysis of Human Matriptase-2 by Kunitz-Type Serine Protease Inhibitors.
  • Lecture at COMSATS, Institute of Information Technology - Abbottabad, Pakistan, September 01, 2014
    M. Gütschow:
    Inhibition of Therapeutically Relevant Human Cysteine Proteases by Azadipeptide Nitriles.
  • Gordon Research Conference - Proteolytic Enzymes & Their Inhibitors - Lucca (Barga) 2014
    Michael Gütschow:
    Inhibition of Human Cysteine Cathepsins by Azapeptide Nitriles.
  • Scientific Winter School Future-Biotech of the Russian Academy of Sciences - Zvenigorod, January 2014
    M. Gütschow:
    How to inhibit therapeutically relevant human cysteine proteases by small molecules.
  • Frontiers in Medicinal Chemistry - Tübingen 2014
    M. Sheikh, M. Steinkrüger, D. Augner, M. Gütschow, S. Herzig, H.-G. Schmalz, M. Pietsch:
    Identification and Kinetic Characterization of 2-Benzyl-3-Phenylisoindolinones as Novel Inhibitors of Human Cholesterol Esterase.
  • ChemBioMed III - Disease Relevant Proteases - Ligands from Nature and from Rational Design - Mainz 2013
    M. Gütschow:
    Azapeptide Nitriles as Inhibitors of Human Cathepsins.
  • Jahrestagung der DPhG – Freiburg 2013
    J. Schmitz, M. Frizler, R. Löser, M. Ponert, U. Bartz, M. Gütschow:
    Development of Dipeptide Nitrile Inhibitors of Cathepsin F.
  • Jahrestagung der DPhG – Freiburg 2013
    M. D. Mertens, J. Schmitz, M. Frizler, M. Gütschow:
    Synthesis and Characterization of a Coumarin-Labeled Vinyl Sulfone as Acitivity Based Probe for Cysteine Cathepsins.
  • Lecture at the Institute of Organic Chemistry, Polish Academy of Sciences – Warsaw, October 8, 2013
    M. Gütschow:
    Azapeptide Nitriles As Inhibitors of Human Cathepsins.
  • 22nd Polish Peptide Symposium - Kudowa Zdroj 2013
    M. Gütschow:
    Azapeptides: Experimental Evidence of Atropisomerism and Synthetic Accesses to Constrained Derivatives.
  • 22nd Polish Peptide Symposium - Kudowa Zdroj 2013
    W. Wysocka, N. Gruba, A. Miecznikowska, J. Popow-Stellmaszyk, M. Gütschow, M. Stirnberg, A. Lesner, K. Rolka:
    Characteristics of Human Matriptase-2 by Combinatorial Chemistry.
  • 22nd Polish Peptide Symposium - Kudowa Zdroj 2013
    A. Gitlin, D. Debowski, N. Karna, A. Łegowska, M. Stirnberg, M. Gütschow, K. Rolka:
    Designing, Synthesis und Enzymatic Activity Studies of Inhibitors of Matriptase-2.
  • 20th International Symposium on Radiopharmaceutical Sciences - Jeju, Korea 2013
    R. Löser, R. Bergmann, M. Frizler, B. Mosch, J. Steinbach, M. Gütschow, J. Pietzsch:
    Radiopharmacological Characterisation of an 18F-Labelled Azadipeptide Nitrile as Novel Probe for Molecular Imaging of the Tumour-Associated Cathepsin Activity.
    ref. J. Label. Compd. Radiopharm. 2013, 56, S390.
  • International Symposium on Advances in Synthetic and Medicinal Chemistry - Moskau 2013
    Anne Stößel, Sonja Hinz, Petra Küppers, Jag Heer, Michael Gütschow, and Christa E. Müller:
    Dual Targeting of Adenosine A2A Receptors and Monoamine Oxidase B by 4H-3,1-Benzothiazin-4-ones.
  • International Symposium on Advances in Synthetic and Medicinal Chemistry - Moskau 2013
    Daniela Häußler, Michael Gütschow:
    Synthesis of bis-Benzamidine Phosphonates as Inhibitors of Matriptase-2.
  • 7th Conference on Experimental and Translational Oncology - Portoroz 2013
    M. Gütschow:
    Cathepsin B as a Therapeutic Target in Cancer: Design of Nitrile-Based Peptidic Inhibitors.
  • Fifth Congress of the International BioIron Society - London 2013
    Marit Stirnberg, Eva Maurer, Michael Gütschow:
    The cell surface protease matriptase-2 cleaves AHSG (fetuin A): A new link between iron homeostasis and diabetes.
    ref. Am. J. Hematol. 2013, 88, E51.
  • Fifth Congress of the International BioIron Society - London 2013
    Eva Maurer, Michael Gütschow, Marit Stirnberg:
    Hepatocyte Growth Factor Activator Inhibitor Type 2 (HAI-2) Modulates Hepcidin Expression by Inhibiting Cell Surface Protease Matriptase-2.
    ref. Am. J. Hematol. 2013, 88, E50.
  • 2nd Annual Conference of the International Chemical Biology Society (ICBS) - Kyoto 2013
    M. Sheikh, M. Steinkrüger, D. Augner, T. Mielke, M. Gütschow, S. Herzig, H.-G. Schmalz, M. Pietsch:
    Kinetic Characterization of Isoindolinones as Novel Inhibitors of Human Cholesterol Esterase
  • Annual Meeting Deutsche Gesellschaft für Experimentelle und Klinische Pharmakologie und Toxikologie - Halle/Saale 2013
    M. Sheikh, M. Steinkrüger, D. Augner, M. Gütschow, S. Herzig, H. G. Schmalz, M. Pietsch:
    Identification and Kinetic Characterization of Novel Inhibitors of Human Cholesterol Esterase as Anti-Atherosclerotic Agents.
    ref. Naunyn-Schmiedeberg´s Arch. Pharmacol. Suppl. 1, 2013, 386, 78.
  • Annual Meeting Deutsche Gesellschaft für Experimentelle und Klinische Pharmakologie und Toxikologie - Halle/Saale 2013
    M. Steinkrüger, D. Augner, T. Mielke, M. Gütschow, S. Herzig, H. G. Schmalz, M. Pietsch:
    Structure-Activity Relationships of Novel 2-Benzyl-3-Phenylisoindolinones as Inhibitors of Cholesterol Esterase.
    ref. Naunyn-Schmiedeberg´s Arch. Pharmacol. Suppl. 1, 2013, 386, 80.
  • Frontiers in Medicinal Chemistry - München 2013
    M. D. Mertens, J. Schmitz, M. Frizler, M. Gütschow:
    Synthesis and Characterization of a Coumarin-Labeled Vinyl Sulfone As Activity-Based Probe for Cysteine Cathepsins.
  • 2nd Meeting of the Paul Ehrlich MedChem Euro-PhD Network – Ljubljana 2012
    Philipp A. Ottersbach, Michael Gütschow:
    Short Lecture: Induction of Chirality: Experimental Evidence of Atropisomerism in Azapeptides.
  • 32nd European Peptide Symposium - Athens 2012
    Magdalena Wysocka, Natalia Gruba, Jadwiga Popow, Adam Lesner, Michael Gütschow, Marit Stirnberg, Krzysztof Rolka:
    Substrate Specificity of Human Matriptase-2.
  • European Iron Club Meeting - Rennes 2012
    Marit Stirnberg, Eva Maurer, Michael Gütschow:
    Short Lecture: Insights into the Ligand Binding Mechanism of Matriptase-2 , the Regulatory Protease of Iron Homeostasis: Possible Substrates and Cleavage Sites.
  • European Iron Club Meeting - Rennes 2012
    Eva Maurer, Michael Gütschow, Marit Stirnberg:
    Short Lecture: Identification of a Hypoxia-Responsive Element in the TMPRSS6 Promoter Region.
  • European Iron Club Meeting - Rennes 2012
    Daniela Häußler, Matthias D. Mertens, Marit Stirnberg, Michael Gütschow:
    Design of Matriptase-2 Inhibitors: Synthesis of a Coumarin-Labeled Bis-Benzamidine.
  • International Workshop on Pharmacology and Pharmaceutical Sciences. University of Tokyo meets University of Bonn – Bonn 2012
    M. Frizler, M. D. Mertens, M. Stirnberg, M. Gütschow:
    Development of Activity-Based Probes for Cysteine Cathepsins
  • International Workshop on Pharmacology and Pharmaceutical Sciences. University of Tokyo meets University of Bonn – Bonn 2012
    D. Häußler, M. D. Mertens, M. Gütschow:
    Design and Synthesis of a Fluorescent-Labeled Bis-benzamidine
  • Uni Bonn Meets Bayer Healthcare – Wuppertal, November 03, 2011
    M. Gütschow:
    Azadipeptide Nitriles as Cysteine Protease Inhibitors: Discovery of a Selective, Subnanomolar Cathepsin K Inhibitor.
  • Uni Bonn Meets Bayer Healthcare – Wuppertal, November 03, 2011
    E. Mauer:
    Direct Regulation of Matriptase-2 (TMPSSS6) by HIF-alpha: Identification of a HRE in the TMPRSS6 Promoter.
  • International Symposium of the German Society for Biochemistry and Molecular Biology, Molecular Life Sciences 2011 – Frankfurt am Main 2011
    E. Maurer, M. T. Sisay, M. Stirnberg, T. Steinmetzer, J. Bajorath, M. Gütschow:
    Insights into Matriptase-2 Substrate Binding and Inhibition Mechanisms.
  • International Symposium of the German Society for Biochemistry and Molecular Biology, Molecular Life Sciences 2011 – Frankfurt am Main 2011
    M. Stirnberg, E. Maurer, M. Gütschow:
    Proteolytic Processing of the Serine Protease Matriptase-2, the Key Regulator of Iron Homeostasis.
  • International Symposium NRW International Graduate School Biotech-Pharma - Bonn 2011
    M. Frizler, M. Mertens, M. Stirnberg, M. Gütschow:
    Development of Selective Mechanism-Based Probes for the Determination of Cathepsin K Activity.
  • 21st Polish Peptide Symposium - Suprasł 2011
    M. Gütschow:
    Peptide Nitriles As Cysteine Protease Inhibitors.
  • Advances in Synthetic and Medicinal Chemistry - St. Petersburg 2011
    M. Frizler, M. Mertens, M. Stirnberg, M. Gütschow:
    Development of Selective Mechanism-Based Probes for the Determination of Cathepsin K Activity.
  • 19th International Symposium on Radiopharmaceutical Sciences (ISRS2011) - Amsterdam 2011
    R. Löser, M. Frizler, R. Bergmann, L. Dombrowski, T. Knieß, M. Gütschow, J. Steinbach:
    Radiolabelled cathepsin inhibitors as potential PET tracers for tumour imaging.
    ref. J. Labelled Compd. Radiopharm., 2011, 54, S190.
  • Frontiers in Medicinal Chemistry - Stockholm 2011
    M. D. Mertens, D. Häußler, U. Neumann, M. Gütschow:
    Synthesis of Coumarin-Labeled Amino Acids As Fluorescent Tools and Application in Fmoc Solid Phase Peptide Synthesis.
  • Lecture at the Faculty of Pharmacy, University of Ljubljana - Ljubljana, June 16, 2011
    M. Gütschow:
    Dipeptide Nitriles As Inhibitors of Cysteine Proteases.
  • Lecture at the Department of Pharmacology, University of Cologne - Cologne, May 31, 2011
    M. Gütschow:
    Cyclic Peptides and Peptide Nitriles As Inhibitors of Proteases.
  • Gemeinsame Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Nuklearmedizin – Bregenz 2011
    R. Löser, M. Frizler, R. Bergmann, L. Dombrowski, T. Knieß, M. Gütschow, J. Steinbach:
    F-18 Labelled Cathepsin Inhibitors As Potential Radiotracers for Tumour Imaging.
  • Manfred Donike Workshop, 29th Cologne Wokshop on Dope Analysis - Köln 2011
    A. K. Orlovius, S. Guddat, M. K. Parr, A. Koch, M. Gütschow, M. Thevis, W. Schänzer:
    Identification and Monitoring of Octopamine Sulfoconjugate in Urine by LC-(ESI)-MS/MS.
  • Jahrestagung der Fachgruppe Pharmazeutische / Medizinische Chemie, Frontiers in Medicinal Chemistry, Joint German-Swiss Meeting on Medicinal Chemistry - Saarbrücken 2011
    P. W. Elsinghorst, M. Rodamer, F. Sörgel, M. Gütschow:
    13C and 2H-labeled Sunitinib and Its N-Desethyl Metabolite: Synthesis, Structure Elucidation and Application to LC-MS/MS Analysis of Human Blood Samples.
  • Lecture Symposium, GRK 804 - Montabaur, February 10/11, 2011
    M. Gütschow:
    Syntheses of Fluorescent Compounds and Applications As Bio(Histo)chemical Tools.
  • The School of Pharmacy and Pharmaceutical Sciences - Trinity College, Dublin, February 4, 2011
    M. Gütschow:
    Dipeptide Nitriles As Inhibitors of Cysteine Proteases.
  • III. International Conference of Heterocyclic Chemistry – Moskau 2010
    M. Frizler, M. Gütschow:
    Development of 1,2,4-Oxadiazole-Containing Nitrile Inhibitors of Human Cysteine Cathepsins.
  • Jahrestagung der DPhG – Braunschweig 2010
    S. Dosa, M. Stirnberg, V. Klaß, D. Häußler, E. Maurer, M. Gütschow:
    Short Lecture: Sulfamoylbenzamidines As Inhibitors of Trypsin-Like Serine Proteases: Active Site Mapping of Matriptase-2, a Key Regulator of Iron Homeostasis.
  • Jahrestagung der DPhG – Braunschweig 2010
    E. Maurer, M. Stirnberg, M. Gütschow:
    Activation of Matriptase-2 in HEK Cells is a Trans-Mechanism.
  • Jahrestagung der DPhG – Braunschweig 2010
    M. T. Sisay, M. Frizler, V. Rodrigo, S. Fustero, J. Bajorath, M. Gütschow:
    Molecular Modeling Studies on the Fluorophilic Properties of the S2 Pocket of Cathepsin B.
  • Jahrestagung der DPhG – Braunschweig 2010
    M. Schlenk, M. Paskaleva, J. Iqbal, J. Gäb, M. Gütschow, C. E. Müller:
    Benzothiazinones: A New Class of Potent A1 Adenosine Receptor Antagonists.
  • Jahrestagung der DPhG – Braunschweig 2010
    P. A. Ottersbach, M. Gütschow:
    Direct Formation of Ring-Fused 1,3-Thiazine-2,4-dithiones From Aromatic o-Amino Carboxylic Acids: Observation of a Carbon Disulfide-Mediated Thionation.
  • Jahrestagung der DPhG – Braunschweig 2010
    M. Mertens, M. Pietsch, M. Gütschow:
    Synthesis of N- and O-Sulfonylated 5,6,7,8-Tetrahydrobenzo[4,5] thieno[2,3-d]pyrimidine / Quinazoline Derivatives and Observation of a N-O Sulfonyl Transfer.
  • Jahrestagung der DPhG – Braunschweig 2010
    C. Mohn, H.-G. Häcker, G. V. Kalayda, M. Gütschow, U. Jaehde:
    MRP Inhibitors Increase Platinum Accumulation Upon Exposure of Tumor Cells to Oxaliplatin.
  • Uni Bonn Meets Bayer Schering Pharma (BSP) – Bonn, September 22/23, 2010
    E. Mauer, M. Stirnberg, M. Gütschow:
    Activation of Matriptase-2 in HEK Cells is a Transactivation Mechanism.
  • Uni Bonn Meets Bayer Schering Pharma (BSP) – Bonn, September 22/23, 2010
    Stefan Dosa, Marit Stirnberg, Verena Klaß, Daniela Häußler, Eva Maurer, Michael Gütschow:
    Sulfamoyl Benzamidines as Arginine Mimetics: Inhibition of Trypsin-Like Serine Proteases and Active-Site Mapping of Matriptase-2.
  • Uni Bonn Meets Bayer Schering Pharma (BSP) – Bonn, September 22/23, 2010
    E. Maurer:
    Ectodomain Shedding of Matriptase-2, the Key Regulator of Iron Homeostasis.
  • Uni Bonn Meets Bayer Schering Pharma (BSP) – Bonn, September 22/23, 2010
    H.-G. Häcker:
    Development of ortho-Substituted Aromatic (Thio)Ureas and Derived Heterocycles As Modulators of P-Glycoprotein and Multidrug Resistance-Associated Protein 1.
  • Uni Bonn Meets Bayer Schering Pharma (BSP) – Bonn, September 22/23, 2010
    M. Gütschow:
    Syntheses of Fluorescent Compounds and Applications As Bio(Histo)chemical Tools. 
  • Lecture at the Institute for Research in Medicine and Pharmaceutical Sciences, Faculty of Pharmacy, University of Lisbon, Lisbon, July 27, 2010
    M. Gütschow:
    Cyclic Peptides and Peptide Nitriles As Inhibitors of Proteases.
  • Lecture at Instituto de Química Orgánica General, CSIC, Madrid, July 07, 2010
    M. Gütschow:
    Dipeptide Nitriles As Inhibitors of Cysteine Proteases.
  • Annual Meeting Deutsche Gesellschaft für Experimentelle und Klinische Pharmakologie und Toxikologie -  Mainz  2010
    C. Both, P. W. Elsinghorst, M. Gütschow, K. Mohr, C. Tränkle:
    Topography of Allosteric Binding of Tacrine/Gallamine-Hybrid Modulators at the Muscarinic M-2 Receptor,
    ref. Naunyn-Schmiedeberg´s Arch. Pharmacol. Suppl. 1, 2010, 381, 14.
  • 7. FENS Forum of European Neuroscience – Amsterdam 2010
    Wolfgang Härtig, Bernd-Reiner Paulke, Johannes Kacza, Jens Grosche, Ute Bauer, Anke Hoffmann, Simone Goldhammer, Paul W. Elsinghorst, Michael Gütschow:
    Biodegradable Nanoparticles Delivering the Fluorescent Acetylcholinesterase Inhibitor PE154: in vivo Labelling of Hippocampal beta-Amyloid in Triple Transgenic Mice.
  • Lecture at Gedeon Richter, Budapest, April 23, 2010
    M. Gütschow:
    Heterobilvalent Compounds Addressing Acetylcholine-Binding Proteins in the CNS.
  • Manfred Donike Workshop, 28th Cologne Wokshop on Dope Analysis - Köln 2010
    M. K. Parr, G. Fußhöller, M. Gütschow, C. Hess, W. Schänzer:
    GC-MS(/MS) Investigations on Long-Term Metabolites of 17-Methyl Steroids,
    ref. in Recent Advances in Doping Analysis (18), W. Schänzer et al. Eds., Sportverlag Strauß - Köln 2010.
  • Manfred Donike Workshop, 28th Cologne Wokshop on Dope Analysis - Köln 2010
    A. K. Orlovius, M. K. Parr, S. Guddat, M. Gütschow, M. Thevis, W. Schänzer:
    Detection of Urinary Phase-I and Phase-II Metabolites of Ephedrine and Oxilofrine by LC-MS/MS,
    ref. in Recent Advances in Doping Analysis (18), W. Schänzer et al. Eds., Sportverlag Strauß - Köln 2010.
  • Jahrestagung CESAR - Heidelberg 2009
    C. Mohn, H.-G. Häcker, E. Ziegler, G. V. Kalayda, M. Gütschow, U. Jaehde:
    Impact of MRP-Mediated Efflux and Intracellular Glutathione Level on Platinum Detoxification.ref. Int. J. Clin. Pharmacol. Ther. 2010, 88, 445-447.
  • Institutskolloquium - Forschungszentrum Dresden Rossendorf, 20. November 2009
    M. Gütschow:
    Cyclic Peptides and Peptide Nitriles as Inhibitors of Proteases.
  • International Symposium Signal Transduction and Disease - Aachen 2009
    Marit Stirnberg, Eva Maurer, Stefan Frank, Tobias Bald, Michael Gütschow:
    Ectodomain Shedding of Matriptase-2, the Key Regulator of Iron Homeostasis.
  • International Symposium of the Graduate College 677: Structure and Molecular Interaction as a Basis for Drug Action - Bonn 2009
    Mihiret T. Sisay, Stephanie Hautmann, Christian Mehner, Gabriele M. König, Jürgen Bajorath, Michael Gütschow:
    Inhibition of Human Leukocyte Elastase by the Cyanobacterial Cyclic Peptides Brunsvicamides A−C.
  • Lecture Symposium of the Research Training Group 804 – Hillesheim 2009
    M. Gütschow:
    Bioactive Cyclic Compounds: Cyclic Peptides - Produced by Cyanobacteria. Heterocycles - Derived from Anthranilic Acid.
  • Jahrestagung der DPhG - Jena 2009
    M. Gütschow:
    Synthetic Entries to Heterocyclic Ligands for GPCRs.
  • Jahrestagung der DPhG - Jena 2009
    A.-K. Orlovius, S. Guddat, M. K. Parr, M. Kohler, M. Gütschow, M. Thevis, W. Schänzer:
    Terbutaline Sulfoconjugate: Characterisation and Urinary Excretion Monitored by LC/ESI-MS/MS.
  • Jahrestagung der DPhG - Jena 2009
    C. Mohn, H.-G. Häcker, E. Ziegler, G. V. Kalayda, M. Gütschow, U. Jaehde:
    Effect of MRP1 and MRP2 Inhibition on Cellular Platinum Concentrations.
  • Jahrestagung der DPhG - Jena 2009
    F. Kanefendt, A. Lindauer, C. Krambeer, P. Di Gion, M. Rodamer, M. Kinzig, F. Sörgel, U. Fuhr, P. W. Elsinghorst, M. Gütschow, U. Jaehde: 
    Short Lecture:  Analysis and PK/PD Modeling of Plasma Biomarkers in Healthy Volunteers after Administration of a Novel Pharmacophore.
  • 38. Deutscher Lebensmittelchemikertag - Berlin 2009
    Paul W. Elsinghorst, Taner Cavler, Anna Müller, Michael Blaut, Annett Braune, Michael Gütschow:
    The Rearrangement of Taxifolin to Alphitonin:Chiral Investigations, ref. Lebensmittelchemie 2010, 64, 105.
  • 3. European Conference on Chemistry for Life Sciences - Frankfurt am Main 2009
    Maxim Frizler, Reik Löser, Friederike Lohr, Michael Gütschow:
    Short Lecture & Poster: Highly Potent and Selective Nitrile Inhibitors with Azadipeptide Scaffold Against Human Papain-Like Cysteine Proteases.
  • Lecture, Fachbereich Chemie, Pharmazie und Geowissenschaften, Universität Mainz - July 6, 2009
    Michael Gütschow:
    Dipeptidnitrile als Inhibitoren von humanen Cysteinproteasen.
  • Workshop - Chemico-Biological Interactions in Proliferation and Differentiation – Köln June 12, 2009
    Michael Gütschow:
    Specific Inhibitors of Proteases and Angiogenesis.
  • Pre-Satellite Meeting of the 2nd Pharmaceutical Sciences Fair & Exhibition (PharmSciFair) – Nice 2009
    Hans-Georg Häcker, Stefan Leyers, Jeanette Wiendlocha, Michael Wiese, Michael Gütschow:
    Short Lecture: Aromatic 2-(Thio)ureidocarboxylic Acids as MRP1 Inhibitors: Synthesis, Biological Evaluation and Identification of a Pharmacophore Pattern.
  • Pharmazentrum-Zentrum Bonn (PZB) meets Bayer Schering Pharma (BSB) – Bonn Mai 19, 2009
    Michael Gütschow:
    Tetrafluorphthalimide und Peptidnitrile als potenzielle Angiogenese- Hemmstoffe.
  • Manfred Donike Workshop, 27th Cologne Wokshop on Dope Analysis - Köln 2009
    A. K. Orlovius, M. K. Parr, S. Guddat, M. Gütschow, M. Thevis, W. Schänzer:
    Urinary Excretion of Terbutaline and its Sulfoconjugated Phase-II Metabolite Monitored by LC-MS/MS,
    ref. in Recent Advances in Doping Analysis (17), W. Schänzer et al. Eds., Sportverlag Strauß - Köln 2009.
  • 8th Göttingen Meeting of the German Neuroscience Society – Göttingen 2009
    W. Härtig, J. Kacza, B. R. Paulke, J. Grosche, A. Hoffmann, P. W. Elsinghorst, M. Gütschow:
    Hippocampal beta-Amyloid Plaques in Triple Transgenic Mice Revealed with a Novel, Fluorescent Acetylcholinesterase Inhibitor Delivered from Nanoparticles.
  • Eröffnungssymposium NRW International Graduate Research School Biotech-Pharma - Bonn, 04.02. 2009
    Maxim Frizler, Friederike Lohr, Michael Gütschow:
    Novel Nitrile Inhibitors for Human Papain-Like Cysteine Proteases: Synthesis and Inhibition Studies.
  • Manfred Donike Workshop, 26th Cologne Wokshop on Dope Analysis - Köln 2008
    M. K. Parr, H. Geyer, M. Gütschow, N. Haenelt, G. Opfermann, M. Thevis, W. Schänzer:
    New Steroids on the "Supplement Market",
    ref. in Recent Advances in Doping Analysis (16), W. Schänzer et al. Eds., Sportverlag Strauß - Köln 2008.
  • Jahrestagung der DPhG - Bonn 2008
    Paul. W. Elsinghorst, Michael Gütschow:
    Oxo- and Halo-Substituted Aminocoumarins: Spectral Properties and Applications in Medicinal Chemistry.
  • Jahrestagung der DPhG - Bonn 2008
    Mihiret Tekeste Sisay, Jürgen Bajorath, Michael Gütschow:
    Covalent Docking of Nitrile-Based Cysteine Protease Inhibitors: Implications for Selective Inhibitor Design.
  • Jahrestagung der DPhG - Bonn 2008
    J. Cieslik, P. W. Elsinghorst, M. Gütschow, J. Ellis, K. Mohr, C. Tränkle:
    Effect of Tacrine-Gallamine Hydrid Allosteric Agents on [3H]Acetylcholine Binding to M2 Receptors.
  • Jahrestagung der DPhG - Bonn 2008
    Maxim Frizler, Reik Löser, Michael Gütschow:
    Formation of Unexpected Heterocycles on the Synthetic Route to Azadipeptide Nitriles.
  • Jahrestagung der DPhG - Bonn 2008
    S. Dosa, M. Gütschow:
    Synthesis of Amidinobenzene Sulfonamides as Potential Inhibitors of Matriptase-2.
  • Jahrestagung der DPhG - Bonn 2008
    A. K. Orlovius, M. K. Parr, S. Guddat, M. Gütschow, M. Thevis, W. Schänzer:
    Phase-II-Metabolism of Stimulants: Characterization of Sulfoconjugates for Advanced Doping Analysis.
  • Jahrestagung der DPhG - Bonn 2008
    Hans-Georg Häcker, Stefan Leyers, Jeanette Wiendlocha, Michael Wiese, Michael Gütschow:
    Aromatic 2-(Thio)ureidocarboxylic Acids as Novel Inhibitors of MRP1.
  • Jahrestagung der DPhG - Bonn 2008
    C. Mehner, D. Müller, S. Kehraus, S. Hautmann, M. Gütschow, G.M. König:
  • New Human Leukocyte Elastase Inhibitors from the Cyanobacterium Nostoc insulare.
    Symposium des Pharma-Zentrums Bonn am 14. August 2008 in Bonn
    Michael Gütschow, Marit Stirnberg, Paul W. Elsinghorst, Hans-Georg Häcker, Mihiret Tekeste Sisay, Stefan Dosa, Maxim Frizler, Friederike Lohr, Philipp A. Ottersbach, Jing Zhou:
    En Route to Small Molecules with Remarkable Bioactivities.
  • Lecture at the Principe Felipe Centro de Investigacion, University of Valencia, Valencia, July 11, 2008
    M. Gütschow:
    Azapeptide Nitriles as Inhibitors of Cathepsins.
  • 6th FENS Forum of European Neuroscience - Genf 2008
    Wolfgang Härtig, J. Kacza, B.R. Paulke, Jens Grosche, A. Hoffmann, Paul W. Elsinghorst, Michael Gütschow:
    Targeting of Hippocampal beta-Amyloid Plaques in Triple Transgenic Mice with a Novel, Fluorescent Acetylcholinesterase Inhibitor Released from Nanoparticles.
  • Pharmazeutisch-lebensmittelchemisches Kolloquium - Westfälische Wilhelms- Universität Münster, 20. Mai 2008
    M. Gütschow:
    Dipeptidnitrile als Cysteinprotease-Inhibitoren.
  • Institutskolloquium - Institut für Pharmazeutische Chemie, Technische Universität Braunschweig, 22. April 2008
    M. Gütschow:
    Dipeptidnitrile als Cysteinprotease-Inhibitoren.
  • 11th International Medical Chemical Defence Conference 2008 - München 2008
    Paul W. Elsinghorst, Wolfgang Härtig, Simone Goldhammer, Jens Grosche, Michael Gütschow:
    PE154 - A Fluorescent Probe for Cholinesterase Imaging.
  • Jahrestagung der Fachgruppe Pharmazeutische / Medizinische Chemie
    Frontiers in Medicinal Chemistry - Regensburg 2008
    Paul W. Elsinghorst, Wolfgang Härtig, Michael Gütschow:
    Short Lecture: Exploring Cholinesterases Inside beta-Amyloid Plaques.
  • Manfred Donike Workshop, 25th Cologne Wokshop on Dope Analysis - Köln 2007
    M. K. Parr, A. K. Orlovius, S. Guddat, M. Gütschow, M. Thevis, W. Schänzer:
    Sulfoconjugates of Heavy Volatile Nitrogen Containing Doping Substancen for Improved LC-MS/MS Screening,
    ref. in Recent Advances in Doping Analysis (15), W. Schänzer et al. Eds., Sportverlag Strauß - Köln 2007.
  • Lecture at the School of Pharmacy and Biochemistry, University of Buenos Aires, Department of Organic Chemistry - November 15, 2007
    M. Gütschow:
    Design and Synthesis of Inhibitors of Serine Esterases.
  • XVI Simposio Nacional de Quimica Organica; Sociedad Argentina de Investigaciones en Quimica Organica - Mar del Plata 2007
    M. Gütschow:
    Synthetic Approaches Towards Novel Inhibitors of Cysteine Proteases.
  • 48th Spring Meeting, Deutsche Gesellschaft für Experimentelle und Klinische Pharmakologie und Toxikologie - Mainz 2007
    Julia Cieslik, Paul W. Elsinghorst, Michael Gütschow, Klaus Mohr und Christian Tränkle:
    Allosteric Modulation in Muscarinic M-2 Receptors: Linkage of Two Allosteric Inhibitor Related Moieties Yields an Allosteric Enhancer.
    ref. Naunyn-Schmiedebergs Arch. Pharmacol. Suppl.1, 2007, 375, 21.
  • Jahrestagung der DPhG in Gemeinschaft mit der Österreichischen Pharmazeutischen Gesellschaft und der Gesellschaft für Arzneipflanzenforschung - Erlangen 2007
    Hans-Georg Häcker, Katja Sterz, Antje de la Haye, Michael Wiese, Michael Gütschow:
    Synthesis of Thieno[2,3-d]pyrimidines as Modulators of P-Glycoprotein.
  • Jahrestagung der DPhG in Gemeinschaft mit der Österreichischen Pharmazeutischen Gesellschaft und der Gesellschaft für Arzneipflanzenforschung - Erlangen 2007
    Stefan Leyers, Jeanette Wiendlocha, Lars Möllmann, Hans-Georg Häcker, Michael Gütschow, Michael Wiese:
    Relevance of MRP2 in Cisplatin Uptake and Identification of Novel Inhibitors of MRP1 and MRP2.
  • Jahrestagung der DPhG in Gemeinschaft mit der Österreichischen Pharmazeutischen Gesellschaft und der Gesellschaft für Arzneipflanzenforschung - Erlangen 2007
    Paul W. Elsinghorst, Wolfgang Härtig, Simone Goldhammer, Michael Gütschow:
    A Novel Fluorescent Probe for Acetylcholinesterase Imaging in β-Amyloid Plaques.
  • Jahrestagung der DPhG in Gemeinschaft mit der Österreichischen Pharmazeutischen Gesellschaft und der Gesellschaft für Arzneipflanzenforschung - Erlangen 2007
    Mihiret Tekeste Sisay, Michael Gütschow, Jürgen Bajorath:
    Homology Modeling and Structural Analysis of the Catalytic Domain of Matriptase-2
  • 5th European Conference on Marine Natural Products - Ischia 2007
    Christian Mehner, Stefan Kehraus, Stephanie Hautmann, Michael Gütschow and Gabriele M. König:
    New Cyclic Peptides from the Cyanobacterium Nostoc insulare
  • Pre-Satellite Meeting of the 3rd Pharmaceutical Sciences World Congress (PSWC 2007) - Amsterdam 2007
    Hans-Georg Häcker, Michael Gütschow:
    Solid Phase Synthesis of Trisubstituted Acylureas Utilizing Carbonyl Insertion Compounds
  • Joint German-Swiss Meeting on Medicinal Chemistry
    Frontiers in Medicinal Chemistry - Berlin 2007
    Paul W. Elsinghorst, Christian Tränkle, Klaus Mohr, Daniela Gündisch, Michael Gütschow:
    Gallamine-Tacrine Hybrids - Synthesis, Inhibition of Cholinesterases and Action on Cholinoreceptors
  • Lecture at the University of Barcelona, Faculty of Pharmacy - March 15, 2007
    M. Gütschow:
    Development of Inhibitors of Serine Hydrolases
  • Vortrag im Institut für Pharmakologie und Toxikologie der Bundeswehr - 28. Februar 2007
    M. Gütschow:
    Entwicklung von niedermolekularen Inhibitoren für Proteasen und Esterasen
  • German Sport University Cologne, Workshop 2007
    M. K. Parr, A. Orlovius, S. Guddat, M. Gütschow, W. Schänzer:
    Combined Screening on Diuretics and Heavy Volatile Nitrogen Containing Doping Substances utilizing LC-MS/MS
  • Vortrag vor der Landesgruppe Berlin-Brandenburg der DPhG - 22. November 2006
    M. Gütschow:
    Enzyminhibitoren in der Therapie von Morbus Parkinson
  • DPhG-Jahrestagung - Marburg 2006
    Camino M. Gonzalez Tanarro, Anastasiya Rybak, Detlef Briel, Michael Gütschow:
    Kinetic and HPLC Investigations on Thienooxazinones As Inhibitors of Human Leukocyte Elastase
  • DPhG-Jahrestagung - Marburg 2006
    Julia Cieslik, Paul W. Elsinghorst, Michael Gütschow, Klaus Mohr, Christian Tränkle:
    Allosteric Actions of the Hybrid Modulator Gü1178 in Muscarinic M2 Receptors
  • DPhG-Jahrestagung - Marburg 2006
    Hans-Georg Häcker, Michael Gütschow:
    Solid Phase Synthesis of Substituted Ureas From Activated Intermediates
  • International Symposium of the Graduate College 677/1: Structure and Molecular Interaction as a Basis for Drug Action - Bonn 2006
    Paul W. Elsinghorst, Klaus Mohr, Christian Tränkle, Michael Gütschow:
    Gallamine-Tacrine Hybrid Inhibitors of Cholinesterases Targeting the M2 Receptor
  • International Symposium of the Graduate College 677/1: Structure and Molecular Interaction as a Basis for Drug Action - Bonn 2006
    Camino M. Gonzalez Tanarro, Anastasiya Rybak, Detlef Briel, Michael Gütschow:
    Thieno[2,3-d]oxazin-4-ones with C-Substituents at 2-Position As Inhibitors of Human Leukocyte Elastase
  • 10th International Medical Chemical Defence Conference 2006 - München 2006
    Paul W. Elsinghorst, Michael Gütschow:
    Novel Hybrid Acetylcholinesterase Inhibitors: Synthesis, Docking and Inhibition Studies
    ref. Toxicology, 2007, 233, 236.
  • Symposium: From Lipids to Lipidomics - Basics, Advances and Applications - Bonn 2006
    Angelika Horstmeyer, Sonja Kolp, Kai Prager, Jochen Walter, Michael Gütschow:
    Shedding of Human Matriptase-2 is Required for Proteolytic Activity
  • DPhG-Jahrestagung - Mainz 2005
    Agnieszka Ambrozak, Ioana Silly, Michael Gütschow:
    Phthalimide Derivatives As Potential Antiangiogenic Agents
  • DPhG-Jahrestagung Mainz - 2005
    Camino M. González Tanarro, Michael Gütschow:
    Kinetic Investigations on Tetracyclic Thieno Compounds As Inhibitors of Acetylcholinesterase
  • DPhG-Jahrestagung - Mainz 2005
    Jürgen Gäb, Silvia Scolari, Christa E. Müller, Michael Gütschow:
    4H-3,1-Benzothiazin-4-ones as Novel Ligands for Adenosine Receptors
  • DPhG-Jahrestagung - Mainz 2005
    Reik Löser, Maxim Frizler, Michael Gütschow:
    Investigations Towards the Synthesis of Aza Analogous Dipeptide Nitriles As Potential Cysteine Protease Inhibitors
  • DPhG-Jahrestagung - Mainz 2005
    Paul Elsinghorst, Michael Gütschow:
    Novel Heterodimeric Tacrine Derivatives Containing a Donepezil-Like Moiety
  • DPhG-Jahrestagung - Mainz 2005
    Sonja Kolp, Kai Prager, Jochen Walter, Michael Gütschow:
    Proteolytic Activity in Membrane Fractions of Matriptase-2 Transfected HEK Cells
  • DPhG-Jahrestagung - Mainz 2005
    Markus Pietsch, Michael Gütschow:
    New Thieno[1,3]oxazin-4-ones As Inhibitors of Cholesterol Esterase and Acetylcholinesterase
  • 9th International Symposium on Proteinase Inhibitors and Biological Control - Brdo, Slovenia 2005
    Sonja Kolp, Kai Prager, Jochen Walter, Michael Gütschow:
    Expression of Membrane-Bound Matriptase-2 in HEK Cells and Determination of the Proteolytic Activity of Membrane Fractions
  • 9th International Symposium on Proteinase Inhibitors and Biological Control - Brdo, Slovenia 2005
    Markus Pietsch, Michael Gütschow:
    New Thieno[1,3]oxazin-4-ones as Inhibitors of Acetylcholinesterase and Leukocyte Elastase
  • 14th International Symposium "Molecular and Physiological Aspects of Regulatory Processes of the Organism" - Krakow, Poland 2005
    M. Gütschow, M. Meusel, T. Librowski, M. Kubacka:
    The Comparative Investigations of Analgesic Activity of New Ureide Derivatives in Some Experimental Models in Rodents
  • 14th International Symposium "Molecular and Physiological Aspects of Regulatory Processes of the Organism" - Krakow, Poland 2005
    M. Gütschow, M. Meusel, T. Librowski, M. Kubacka:
    The Influence of New Ureide Derivatives on the Central Nervous System Activity in Mice
  • 2nd UK Nicotinic Receptor Club Meeting - Harlow, Essex 2005
    M. Andrä, L. Munoz, C. Tilotta, M. Pietsch, M. Seleshi, C. Gonzalez, T. Suzuki, A. Matsubara, I. Hide, H. Matsubayashi, N. Sakai, H. Bönisch, M. Gütschow, D. Gündisch:
    Phenylcarbamates as Ligands for Nicotinic Acetylcholine Receptors (nAChR)
  • DPhG-Doktorandentagung - Leipzig 2005
    Camino M. Gonzalez Tanarro, Michael Gütschow:
    Synthesis and Enzyme Kinetics of Tetracyclic Acetylcholinesterase Inhibitors
  • DPhG-Doktorandentagung - Leipzig 2005
    Manuela Meusel, Michael Gütschow:
    Vortrag: Darstellung von N-Acylharnstoffen in Lösung und an fester Phase
  • DPhG-Jahrestagung - Joint Meeting - Regensburg 2004
    M. Gonzales Tanarro, Michael Gütschow:
    HPLC Investigations on Acylating Inhibitors of Serine Hydrolases
  • DPhG-Jahrestagung - Joint Meeting - Regensburg 2004
    Sonja Kolp, Michael Gütschow:
    Influence of Compatible Solutes on Enteropeptidase-Catalyzed Processing of Trypsinogen
  • DPhG-Jahrestagung - Joint Meeting - Regensburg 2004
    Markus Pietsch, Michael Gütschow:
    New Thieno-1,3-oxazin-4-ones as Inhibitors of Acetylcholinesterase and Leukocyte Elastase
  • DPhG-Jahrestagung - Joint Meeting - Regensburg 2004
    Paul W. Elsinghorst, Michael Gütschow:
    N-Acylpyrrolidin-2-ones: Potential inhibitors of serine proteases and esterases
  • DPhG-Jahrestagung - Joint Meeting - Regensburg 2004
    Reik Löser, Klaus Schilling, Elke Dimmig, Michael Gütschow:
    Short lecture: Interaction of the Cathepsins L, S, K and Papain with Dipeptide-Derived Nitriles
  • DPhG-Jahrestagung - Joint Meeting - Regensburg 2004
    Agnieszka Ambrozak, Michael Gütschow:
    Phthalimido- and Tetrafluorophthalimidobarbituric Acids as Potential Antiangiogenic Agents
  • DPhG-Jahrestagung - Joint Meeting - Regensburg 2004
    Manuela Meusel, Michael Gütschow:
    Novel Syntheses of N-Acylureas: From Solution to Solid-Phase Chemistry
  • 4th International Conference on Cysteine Proteinases and their Inhibitors - Portoroz, Slovenia 2004
    Reik Löser, Klaus Schilling, Elke Dimmig, Michael Gütschow:
    Interaction of the Cathepsins L, S, K and Papain with Dipeptide-Derived Nitriles
  • Biochemisches Kolloquium - Universität Leipzig, Institut für Biochemie 13. April 2004
    M. Gütschow:
    Mechanismus-orientierte Inhibitoren von Serin- und Cystein-Hydrolasen
  • 95th Annual Meeting of the American Association for Cancer Research - Orlando 2004
    Sylvia S. W. Ng, Michael Gütschow, Kurt Eger, William D. Figg:
    Antitumor Effects of Thalidomide Analogues in Human Prostate Cancer Xenografts Implanted in Immunodeficient Mice
  • 16th International Mass Spectrometry Conference (IMSC 2003) - Edinburgh 2003
    Wolfram Engst, Annett Braune, Michael Gütschow, Michael Blaut:
    HPLC/ESI-MS-MS Analysis of Metabolites of Quercetin and Luteolin Formed By the Human Gut Bacterium Eubacterium ramulus
    ref. Adv. Mass. Spectrom. 16 (2003) S292
  • 32. Konference Synteza a Analyza Leciv - Meeting of the Czech and Slovakian Pharmaceutical Societies - Velke Karlovice 2003
    Marta Chlupacova, Reik Löser, Ales Marecek, Veronika Opletalova, Michael Gütschow:
    Synthesis of 2-Benzyl-2-hydroxybenzofuran-3(2H)-one, a Natural Substance Isolated From Flindersia brassii
  • Polish-Austrian-German-Hungarian-Italian Joint Meeting on Medicinal Chemistry - Krakow 2003
    Agnieszka Ambrozak, Manuela Meusel, Michael Gütschow:
    A New Synthetic Route to 1,3,5,5-Tetrasubstituted Hydantoins via Rearrangement of 5-Aminobarbituric Acids
  • Polish-Austrian-German-Hungarian-Italian Joint Meeting on Medicinal Chemistry - Krakow 2003
    Sonja Kolp, Markus Pietsch, Erwin A. Galinski, Michael Gütschow:
    Protection against Proteolytic Cleavage by Compatible Solutes
  • Polish-Austrian-German-Hungarian-Italian Joint Meeting on Medicinal Chemistry - Krakow 2003
    Reik Löser, Klaus Schilling, Michael Gütschow:
    Interaction of Papain-Like Cysteine Proteases with Dipeptide-Derived Nitriles
  • Polish-Austrian-German-Hungarian-Italian Joint Meeting on Medicinal Chemistry - Krakow 2003
    Manuela Meusel, Michael Gütschow:
    Investigations on Mechanisms of the Aminobarbituric Acid-Hydantoin Rearrangement
  • Polish-Austrian-German-Hungarian-Italian Joint Meeting on Medicinal Chemistry - Krakow 2003
    Markus Pietsch, Kathleen Taubert, Bärbel Schulze, Michael Gütschow:
    Inhibition of Human Leukocyte Elastase by 2-Phenylisothiazol-3(2H)-one 1,1-Dioxides
  • Jahrestagung der Deutschen Pharmazeutischen Gesellschaft (DPhG) - Würzburg 2003
    Manuela Meusel, Michael Gütschow:
    Investigations on Mechanisms of the Aminobarbituric Acid-Hydantoin Rearrangement
  • International Symposium of the Graduate College 677/1: Structure and Molecular Interaction as a Basis for Drug Action - Bonn 2003
    Markus Pietsch, Michael Gütschow:
    New Tetrahydropyrido-anellated Thieno-1,3-oxazin-4-ones as Inhibitors of Acetylcholinesterase and Leukocyte Elastase
  • 6th German Peptide Symposium - Berlin 2003
    Reik Löser, Michael Gütschow:
    Interaction of Papain and Papain-Like Cysteine Proteases with Dipeptide-Derived Nitriles
  • 225th ACS National Meeting - New Orleans 2003
    Frederick A. Luzzio, Sylvia S. W. Ng, Michael Gütschow, Sunna Hauschildt, Michael Weiss, Uwe Teubert, Erwin Kruger, Alexander V. Mayorov, Kurt Eger, William D. Figg:
    Antiangiogenic Activity of N-Substituted and Tetrafluorinated Thalidomide Analogs.
  • Doktorandentagung der Deutschen Pharmazeutischen Gesellschaft (DPhG) - Düsseldorf 2003
    Agnieszka Ambrozak, Manuela Meusel, Michael Gütschow
    Darstellung von 5-Carbamoylhydantoinen durch Umlagerung von 5-Aminobarbitursäuren
  • 13th EORTC-AACR-NCI Symposium on Molecular Targets and Cancer Therapeutics - Frankfurt/Main 2002
    Sylvia S. W. Ng, Erwin A. Kruger, Frederick A. Luzzio, Kurt Eger, Michael Gütschow, Sunna Hauschildt, Thomas K. Hecker, Uwe Teubert, Michael Weiss, William, D. Figg:
    In Vitro Antiangiogenic Activity of Thalidomide Analogues.
    ref. Eur. J. Cancer, 2002, 263, S82.
  • Jahrestagung der Deutschen Pharmazeutischen Gesellschaft (DPhG) - Berlin 2002
    Abdelzim Sarhan, Markus Pietsch, Michael Gütschow:
    Studies on the Enzymatic Hydrolysis of 5-Benzylhydantoins by D-Hydantoinase from Vigna angularis
  • Jahrestagung der Deutschen Pharmazeutischen Gesellschaft (DPhG) - Berlin 2002
    Markus Pietsch, Kathleen Taubert, Bärbel Schulze, Michael Gütschow:
    Inhibition of Human Leukocyte Elastase by 2-Phenylisothiazol-3(2H)-one 1,1-Dioxides
  • Dionex-Anwendertreffen ASE/HPLC - Trier 2002
    Abdelazim Sarhan, Markus Pietsch, Michael Gütschow:
    Untersuchungen zur D-Hydantoinase-katalysierten Hydrolyse von 5-Benzylhydantoin
  • 1. Workshop des Projektverbundes ETTT (Enzyme - Tools, Targets, Therapeutics) - Saarbrücken 12.-13. Dezember 2001
    Michael Gütschow:
    Hauptvortrag: Interaction of Serine Hydrolases with Low-Molecular Weight Inhibitors
  • Jahrestagung der Deutschen Pharmazeutischen Gesellschaft (DPhG) - Halle 2001
    Markus Pietsch and Michael Gütschow:
    Thieno[2,3-d]oxazin-4-ones as Alternate Substrate Inhibitors of Pancreatic Cholesterol Esterase
  • Herbsttagung der Gesellschaft für Biochemie und Molekularbiologie (GBM) - Bochum 2001
    Markus Pietsch, Sylvia Kaap, Michael Gütschow:
    Interactions of Pancreatic Cholesterol Esterase with Alternate Substrates
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